Vol 3-2 Research Article

The Effects of Caloric Restriction and/or Intermittent Fasting on Bone Health

Connor A. Hernon1,2, Abduallah Elsayed3, Raphael M. Vicente4, Ariane Zamarioli4, Melissa A. Kacena3,5,6, Jonathan W. Lowery1,2,3,5,6

1Division of Biomedical Science, Marian University College of Osteopathic Medicine, Indianapolis, Indiana, USA

2Bone & Muscle Research Group, Marian University, Indianapolis, Indiana USA

3Department of Orthopaedic Surgery, Indiana University School of Medicine, Indiana, USA

4Department of Orthopaedics and Anaesthesiology, Ribeirão Preto Medical School, University of São Paulo, SP, Brazil

5Richard L. Roudebush VA Medical Center, IN, USA

6Indiana Center for Musculoskeletal Health, School of Medicine, Indiana University, Indianapolis, Indiana, USA

This mini-review summarizes the available information regarding the impact of caloric restriction (CR) and/or intermittent fasting (IF) on bone health. CR and IF are dietary interventions used in rehabilitative healthcare for augmenting weight loss and also proposed for recovery of conditions such as stroke and heart failure. CR restricts the total number of calories rather than different food groups or periods of eating. In contrast, IF severely restricts caloric intake for a period of time followed by a period of ad libitum intake. Here, we discuss the available information regarding the impact of these rehabilitation diets on bone metabolism, highlighting areas of consistency and discrepancy and suggesting future areas of study to advance the understanding of CR and/or IF on bone health.

DOI: 10.29245/2767-5122/2021/2.1128 View / Download Pdf
Vol 3-2 Research Article

Validation of the Comprehensive Arm Prosthesis and Rehabilitation Outcomes Questionnaire

Kerstin S. Baun1, Nathan T. Kearns2, Jennifer K. Peterson1, John M. Miguelez1

1Clinical Services, Advanced Arm Dynamics, Redondo Beach, CA, USA

2Department of Psychology, University of North Texas, Denton, TX, USA

Purpose: To develop and psychometrically evaluate the Comprehensive Arm Prosthesis and Rehabilitation Outcomes Questionnaire (CAPROQ), a 28-item, self-report measure of three key facets associated with successful rehabilitation (perceived function, satisfaction, and pain) designed specifically for the adult upper limb loss (ULL) population.

Materials and Methods: Using a national sample of adult ULL patients (N=240), factor structure, internal consistency, convergent/concurrent validity, and known group validity of the total CAPROQ score and three subscale scores were evaluated.

Results: Confirmatory factor analysis indicated adequate-to-strong factor loading on each subscale: satisfaction (.623-.913), perceived function (.572-.860) and pain (.422-.834).  Internal consistencies for the total measure and measure subscales were good-to-excellent (.89-.95) and convergent validity indicated moderate-to-strong statistically significant associations between the CAPROQ subscales and relevant measures. Concurrent validity showed moderate associations between CAPROQ total score, prosthetic wear time, and psychosocial adjustment scores. Known group validity indicated significant differences on CAPROQ total score between initial and definitive fitting stages (p=.012).

Conclusion: Psychometric evaluation indicated that the CAPROQ and CAPROQ subscales were structurally sound, internally consistent, and demonstrated convergent validity with currently used assessments of perceived functioning, satisfaction, and pain.  CAPROQ is needed for guiding individual patient care, improving care models and future prosthesis selection and development.

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