Vol 3-1 Systematic Review

The association between sarcopenia and the physical function of patients with stroke: A systematic review and meta-analysis

Irene J Su*, Yi Li, Li Chen

Shantou University Medical College, 22 Xinling Road, Shantou 515041, Guangdong Province, China

Objectives: The purpose of this study is to identify whether there is an association between sarcopenia and physical function outcomes of patients with stroke.

Methods: A systematic search of Pubmed, Web of Science, Cochrane Library, Embase, China National Knowledge Infrastructure (CNKI), and Wanfang database was conducted to identify studies in Chinese and English from the inception of the database to March 2021. Documents were checked for relevancy. Articles exploring the association between sarcopenia and the physical function of patients with stroke were included. The quality of the literature was evaluated using the Newcastle-Ottawa scale tool. Stata 15.0 software was used to conduct meta-analysis.

Results: Eight studies met the criteria for inclusion. A meta-analysis of four studies showed that sarcopenia was related to an increased risk of poor physical function of patients with stroke (total OR=3.11, 95% CI: 2.22-4.34, P<0.0001). Descriptive analysis was performed in the rest of studies. Overall, a correlation between the two factors was found in patients with stroke. Some studies suggested a difference based on gender and severity of the disease condition. The studies included in this review were of high methodological quality. The Egger's test (P=0.217) showed no publication bias.

Conclusions: This review concludes that sarcopenia is an independent predictive factor of physical function of patients with stroke. Clinicians should pay attention to gender differences and severity of disease condition. Therefore, screening, diagnosis, treatment, and prevention of sarcopenia should be part of the routine clinical practice when providing care to stroke patients.

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Vol 3-1 Mini Review Article

What did we learn from a Community Bone Health Promotion Project for People with Mental Retardation?

K.F. Cheng1, Lee Sze Nga2, P. C. Leung1,3*

1 Centre for Clinical Trials on Chinese Medicine, Institute of Chinese Medicine, The Chinese University of Hong Kong, Hong Kong

2 Grace Rehabilitation Service, Evangelical Lutheran Church Social Service - Hong Kong, Hong Kong

3 State Key Laboratory of Research on Bioactivities and Clinical Applications of Medicinal Plants (The Chinese University of Hong Kong), Hong Kong

Background: The Community Bone Health Promotion Project offered service to the individual Mentally Retarded person (MR) together with his/ her personal care-givers as a unit.  The MR tends to get old and suffer from chronic diseases much earlier than the general population. The care-giving parent is older by age and yet could serve as a “control” in the assessment exercises.

Methods: The project took a multidisciplinary approach participated by the social workers, medical experts, nurses and therapists to ensure support and compliance. The promotion of bone health was executed through ordinary physical exercises, machine-driven trainings and dietary support. A special dietary supplement with Traditional Chinese Medicine orientation was chosen for the clients who were expected to have extra appreciation because of the cultural heritage.

The project lasted 12 months after which the assessments included objective measurements of Bone Mineral Density (BMD) and subjective evaluation of Quality of Life (QoL).

Results: Of the 136 participants, 55 were patients with MR and 81 were caregivers. The average age of patients with MR was 52.7 years old, and that of caregivers was 62.2 years old. Compliance of the clients and their caregivers had been very good and great appreciations were expressed. The special dietary supplement with medicinal herb extracts was well loved by both MRs and caregivers. BMD, as expected, did not show significant change after 12 months although a trend of improvement was obvious among the more deficient individuals. Caregivers of older ages could be more responsive compared with the younger MRs.

In conclusion, it was a fruitful project endorsing the multidisciplinary approach in the planning, executions, supervision and assessment. The improvements in Physical functioning, Role physical and Role emotional were shown in the Quality of Life evaluation, further supported the enthusiasm and appreciation of the MRs and their caregivers.

DOI: 10.29245/2767-5122/2021/1.1119 View / Download Pdf